Venoms are complex mixtures of toxic compounds delivered by bite or sting.In humans, the consequences of envenomation range from self-limiting to lethal.Critical host defence against envenomation comprises innate and adaptive immune strategies targeted towards venom detection, neutralisation, detoxification, and symptom resolution.In some instances
Defects in chromatin modifiers and remodelers have been described both for hematological and solid malignancies, corroborating and strengthening the role of epigenetic aberrations in the etiology of cancer.Furthermore, epigenetic marks-DNA methylation, histone modifications, chromatin remodeling, and microRNA-can be considered potential markers of
Abstract Background Shi Zheng (SZ, syndrome of dampness) is a major syndrome type in traditional Chinese Medicine (TCM), the ambiguity of its pathomechanism and the lack of blood diagnostic indicators have limited the understanding of the development of SZ.Purpose To explore the pathological mechanism of SZ and establish a symptom-centered diagnosi
Superficial siderosis (SS) of the nervous system is a rare acquired condition related to hemosiderin deposits in subpial layers of the brain, brainstem, cerebellum, cranial nerves, and Dough Dockers spinal cord, leading to brain iron-mediated neurodegeneration.The cardinal neurological features are slowly progressive hearing loss, ataxia, and pyram
Introduction: Arteriovenous malformations (AVMs) are rare, especially in elderly patients.Occasionally, AVM can produce aneurysmal degenerations, which can lead to bleeding or rupture.The aim of this case report was to describe the surgical treatment of large arterial and venous aneurysms in the arm associated with an AVM.Report: An 83 year old wom